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In Vitro Identification of Novel Plasminogen-Binding Receptors of the Pathogen Leptospira interrogans

BACKGROUND: Leptospirosis is a multisystem disease caused by pathogenic strains of the genus Leptospira. We have reported that Leptospira are able to bind plasminogen (PLG), to generate active plasmin in the presence of activator, and to degrade purified extracellular matrix fibronectin. METHODOLOGY...

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Detalles Bibliográficos
Autores principales: Vieira, Monica L., Atzingen, Marina V., Oliveira, Tatiane R., Oliveira, Rosane, Andrade, Daniel M., Vasconcellos, Silvio A., Nascimento, Ana L. T. O.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889836/
https://www.ncbi.nlm.nih.gov/pubmed/20582320
http://dx.doi.org/10.1371/journal.pone.0011259