Efficient Generation of Germ Line Transmitting Chimeras from C57BL/6N ES Cells by Aggregation with Outbred Host Embryos

Genetically modified mouse strains derived from embryonic stem (ES) cells have become essential tools for functional genomics and biomedical research. Large scale mutagenesis projects are producing libraries of mutant C57BL/6 (B6) ES cells to enable the functional annotation of every gene of the mou...

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Detalles Bibliográficos
Autores principales: Gertsenstein, Marina, Nutter, Lauryl M. J., Reid, Tammy, Pereira, Monica, Stanford, William L., Rossant, Janet, Nagy, Andras
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889837/
https://www.ncbi.nlm.nih.gov/pubmed/20582321
http://dx.doi.org/10.1371/journal.pone.0011260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889837/
https://www.ncbi.nlm.nih.gov/pubmed/20582321
http://dx.doi.org/10.1371/journal.pone.0011260

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