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Minocycline inhibits glial proliferation in the H-Tx rat model of congenital hydrocephalus

BACKGROUND: Reactive astrocytosis and microgliosis are important features of the pathophysiology of hydrocephalus, and persistent glial "scars" that form could exacerbate neuroinflammation, impair cerebral perfusion, impede neuronal regeneration, and alter biomechanical properties. The pur...

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Detalles Bibliográficos
Autores principales: McAllister, James P, Miller, Janet M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889858/
https://www.ncbi.nlm.nih.gov/pubmed/20507614
http://dx.doi.org/10.1186/1743-8454-7-7