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Differential cytokine regulation by NF-κB and AP-1 in Jurkat T-cells
BACKGROUND: Activator protein (AP)-1 and nuclear factor (NF)-κB largely control T-cell activation, following binding of foreign antigens to the T-cell receptor leading to cytokine secretion. Elevated levels of pro-inflammatory cytokines and chemokines such as TNF, IL-6 and CXCL8 are associated with...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889865/ https://www.ncbi.nlm.nih.gov/pubmed/20507572 http://dx.doi.org/10.1186/1471-2172-11-26 |