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PPARγ deficiency results in reduced lung elastic recoil and abnormalities in airspace distribution

BACKGROUND: Peroxisome proliferator-activated receptor (PPAR)-γ is a nuclear hormone receptor that regulates gene expression, cell proliferation and differentiation. We previously described airway epithelial cell PPARγ deficient mice that develop airspace enlargement with decreased tissue resistance...

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Detalles Bibliográficos
Autores principales: Simon, Dawn M, Tsai, Larry W, Ingenito, Edward P, Starcher, Barry C, Mariani, Thomas J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889874/
https://www.ncbi.nlm.nih.gov/pubmed/20525205
http://dx.doi.org/10.1186/1465-9921-11-69