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PPARγ deficiency results in reduced lung elastic recoil and abnormalities in airspace distribution
BACKGROUND: Peroxisome proliferator-activated receptor (PPAR)-γ is a nuclear hormone receptor that regulates gene expression, cell proliferation and differentiation. We previously described airway epithelial cell PPARγ deficient mice that develop airspace enlargement with decreased tissue resistance...
Autores principales: | Simon, Dawn M, Tsai, Larry W, Ingenito, Edward P, Starcher, Barry C, Mariani, Thomas J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889874/ https://www.ncbi.nlm.nih.gov/pubmed/20525205 http://dx.doi.org/10.1186/1465-9921-11-69 |
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