Decreased transcription-coupled nucleotide excision repair capacity is associated with increased p53- and MLH1-independent apoptosis in response to cisplatin

BACKGROUND: One of the most commonly used classes of anti-cancer drugs presently in clinical practice is the platinum-based drugs, including cisplatin. The efficacy of cisplatin therapy is often limited by the emergence of resistant tumours following treatment. Cisplatin resistance is multi-factoria...

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Detalles Bibliográficos
Autores principales: Stubbert, Lawton J, Smith, Jennifer M, McKay, Bruce C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889890/
https://www.ncbi.nlm.nih.gov/pubmed/20470425
http://dx.doi.org/10.1186/1471-2407-10-207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889890/
https://www.ncbi.nlm.nih.gov/pubmed/20470425
http://dx.doi.org/10.1186/1471-2407-10-207

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