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Pharmacokinetic properties and antitumor efficacy of the 5-fluorouracil loaded PEG-hydrogel
BACKGROUND: We have studied the in vitro and in vivo utility of polyethylene glycol (PEG)-hydrogels for the development of an anticancer drug 5-fluorouracil (5-FU) delivery system. METHODS: A 5-FU-loaded PEG-hydrogel was implanted subcutaneously to evaluate the drug retention time and the anticancer...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889891/ https://www.ncbi.nlm.nih.gov/pubmed/20482808 http://dx.doi.org/10.1186/1471-2407-10-211 |