The distribution of the therapeutic monoclonal antibodies cetuximab and trastuzumab within solid tumors

BACKGROUND: Poor distribution of some anticancer drugs in solid tumors may limit their anti-tumor activity. METHODS: Here we used immunohistochemistry to quantify the distribution of the therapeutic monoclonal antibodies cetuximab and trastuzumab in relation to blood vessels and to regions of hypoxi...

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Detalles Bibliográficos
Autores principales: Lee, Carol M, Tannock, Ian F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889896/
https://www.ncbi.nlm.nih.gov/pubmed/20525277
http://dx.doi.org/10.1186/1471-2407-10-255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889896/
https://www.ncbi.nlm.nih.gov/pubmed/20525277
http://dx.doi.org/10.1186/1471-2407-10-255

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