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The distribution of the therapeutic monoclonal antibodies cetuximab and trastuzumab within solid tumors
BACKGROUND: Poor distribution of some anticancer drugs in solid tumors may limit their anti-tumor activity. METHODS: Here we used immunohistochemistry to quantify the distribution of the therapeutic monoclonal antibodies cetuximab and trastuzumab in relation to blood vessels and to regions of hypoxi...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889896/ https://www.ncbi.nlm.nih.gov/pubmed/20525277 http://dx.doi.org/10.1186/1471-2407-10-255 |