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Importance of replication in analyzing time-series gene expression data: Corticosteroid dynamics and circadian patterns in rat liver

BACKGROUND: Microarray technology is a powerful and widely accepted experimental technique in molecular biology that allows studying genome wide transcriptional responses. However, experimental data usually contain potential sources of uncertainty and thus many experiments are now designed with repe...

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Detalles Bibliográficos
Autores principales: Nguyen, Tung T, Almon, Richard R, DuBois, Debra C, Jusko, William J, Androulakis, Ioannis P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889936/
https://www.ncbi.nlm.nih.gov/pubmed/20500897
http://dx.doi.org/10.1186/1471-2105-11-279