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Localization of BDNF mRNA with the Huntington's disease protein in rat brain

BACKGROUND: Studies have implicated reduced levels of brain-derived neurotrophic factor (BDNF) in the pathogenesis of Huntington's disease. Mutant huntingtin (Htt) protein was previously reported to decrease BDNF gene transcription and axonal transport of BDNF. We recently showed that wild-type...

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Detalles Bibliográficos
Autores principales: Ma, Bin, Culver, Brady P, Baj, Gabriele, Tongiorgi, Enrico, Chao, Moses V, Tanese, Naoko
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889995/
https://www.ncbi.nlm.nih.gov/pubmed/20507609
http://dx.doi.org/10.1186/1750-1326-5-22