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Patterns of basal signaling heterogeneity can distinguish cellular populations with different drug sensitivities

Phenotypic heterogeneity has been widely observed in cellular populations. However, the extent to which heterogeneity contains biologically or clinically important information is not well understood. Here, we investigated whether patterns of basal signaling heterogeneity, in untreated cancer cell po...

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Detalles Bibliográficos
Autores principales: Singh, Dinesh Kumar, Ku, Chin-Jen, Wichaidit, Chonlarat, Steininger, Robert J, Wu, Lani F, Altschuler, Steven J
Formato: Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890326/
https://www.ncbi.nlm.nih.gov/pubmed/20461076
http://dx.doi.org/10.1038/msb.2010.22