Prevalence and Determinant Factors of Sarcopenia in Patients With Type 2 Diabetes: The Korean Sarcopenic Obesity Study (KSOS)

OBJECTIVE: We examined prevalence of sarcopenia in Korean patients with type 2 diabetes and compared body compositional parameters between subjects with and without type 2 diabetes. RESEARCH DESIGN AND METHODS: The Korean Sarcopenic Obesity Study (KSOS) included 810 subjects (414 patients with diabe...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Tae Nyun, Park, Man Sik, Yang, Sae Jeong, Yoo, Hye Jin, Kang, Hyun Joo, Song, Wook, Seo, Ji A., Kim, Sin Gon, Kim, Nan Hee, Baik, Sei Hyun, Choi, Dong Seop, Choi, Kyung Mook
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890348/
https://www.ncbi.nlm.nih.gov/pubmed/20413515
http://dx.doi.org/10.2337/dc09-2310
Descripción
Sumario:OBJECTIVE: We examined prevalence of sarcopenia in Korean patients with type 2 diabetes and compared body compositional parameters between subjects with and without type 2 diabetes. RESEARCH DESIGN AND METHODS: The Korean Sarcopenic Obesity Study (KSOS) included 810 subjects (414 patients with diabetes and 396 control subjects) who were examined using dual-energy X-ray absorptiometry. Prevalence of sarcopenia was defined using the skeletal muscle index (SMI). RESULTS: Prevalence in patients with diabetes and in the control group was 15.7 and 6.9%, respectively. In both men and women, SMI values were significantly decreased in patients with diabetes compared with subjects without diabetes. Furthermore, multiple logistic regression analysis showed that type 2 diabetes was independently associated with sarcopenia. CONCLUSIONS: Type 2 diabetes was associated with increased risk of sarcopenia. These characteristics may contribute to physical disability and metabolic disorders in older adults with diabetes.