A Single Nucleotide Polymorphism in STK11 Influences Insulin Sensitivity and Metformin Efficacy in Hyperinsulinemic Girls With Androgen Excess

OBJECTIVE: Serine-threonine kinase STK11 catalyzes the AMP-activated protein kinase complex. We tested the hypothesis that a gene variant in STK11 contributes to variation in insulin sensitivity and metformin efficacy. RESEARCH DESIGN AND METHODS: We studied the effects of a single nucleotide polymo...

Descripción completa

Detalles Bibliográficos
Autores principales: López-Bermejo, Abel, Díaz, Marta, Morán, Erica, de Zegher, Francis, Ibáñez, Lourdes
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890356/
https://www.ncbi.nlm.nih.gov/pubmed/20357370
http://dx.doi.org/10.2337/dc09-1750

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890356/
https://www.ncbi.nlm.nih.gov/pubmed/20357370
http://dx.doi.org/10.2337/dc09-1750

Ejemplares similares