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A Single Nucleotide Polymorphism in STK11 Influences Insulin Sensitivity and Metformin Efficacy in Hyperinsulinemic Girls With Androgen Excess

OBJECTIVE: Serine-threonine kinase STK11 catalyzes the AMP-activated protein kinase complex. We tested the hypothesis that a gene variant in STK11 contributes to variation in insulin sensitivity and metformin efficacy. RESEARCH DESIGN AND METHODS: We studied the effects of a single nucleotide polymo...

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Detalles Bibliográficos
Autores principales:	López-Bermejo, Abel, Díaz, Marta, Morán, Erica, de Zegher, Francis, Ibáñez, Lourdes
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2010
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890356/ https://www.ncbi.nlm.nih.gov/pubmed/20357370 http://dx.doi.org/10.2337/dc09-1750

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