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R-Ras Regulates Migration through an Interaction with Filamin A in Melanoma Cells

BACKGROUND: Changes in cell adhesion and migration in the tumor microenvironment are key in the initiation and progression of metastasis. R-Ras is one of several small GTPases that regulate cell adhesion and migration on the extracellular matrix, however the mechanism has not been completely elucida...

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Detalles Bibliográficos
Autores principales: Gawecka, Joanna E., Griffiths, Genevieve S., Ek-Rylander, Barbro, Ramos, Joe W., Matter, Michelle L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890414/
https://www.ncbi.nlm.nih.gov/pubmed/20585650
http://dx.doi.org/10.1371/journal.pone.0011269