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The roles of p38MAPK and caspase-3 in DADS-induced apoptosis in human HepG2 cells

OBJECTIVES: To explore the function of p38MAPK and caspase-3 in DADS-induced apoptosis in human HepG2 cells, and discuss the signal transduetion mechanism of HepG2 cells in the apoptosis process induced by DADS by using the inhibitors of p38MAPK (SB203580) and caspase-3 (Z-DEVD-FMK). METHODS: After...

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Detalles Bibliográficos
Autores principales: Ji, Chunxiao, Ren, Fenglian, Ma, Heng, Xu, Ming
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890544/
https://www.ncbi.nlm.nih.gov/pubmed/20478073
http://dx.doi.org/10.1186/1756-9966-29-50