Transcriptomic analysis of dystrophin RNAi knockdown reveals a central role for dystrophin in muscle differentiation and contractile apparatus organization

BACKGROUND: Duchenne muscular dystrophy (DMD) is a fatal muscle wasting disorder caused by mutations in the dystrophin gene. DMD has a complex and as yet incompletely defined molecular pathophysiology hindering development of effective ameliorative approaches. Transcriptomic studies so far conducted...

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Detalles Bibliográficos
Autores principales: Ghahramani Seno, Mohammad M, Trollet, Capucine, Athanasopoulos, Takis, Graham, Ian R, Hu, Pingzhao, Dickson, George
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890566/
https://www.ncbi.nlm.nih.gov/pubmed/20515474
http://dx.doi.org/10.1186/1471-2164-11-345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890566/
https://www.ncbi.nlm.nih.gov/pubmed/20515474
http://dx.doi.org/10.1186/1471-2164-11-345

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