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Cotylenin A inhibits cell proliferation and induces apoptosis and PAX6 mRNA transcripts in retinoblastoma cell lines

PURPOSE: Retinoblastoma, a childhood cancer of the retina, is caused by inactivation of the tumor suppressor gene retinoblastoma (RB). Cotylenin A (CN-A), a novel fusicoccane-diterpene glycoside, accelerates the differentiation of several types of myeloid cell lines and is a candidate for a new type...

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Detalles Bibliográficos
Autores principales: Kashiwagi, Yoshiko, Kato, Nobuo, Sassa, Takeshi, Nishitsuka, Koichi, Yamamoto, Teiko, Takamura, Hiroshi, Yamashita, Hidetoshi
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890574/
https://www.ncbi.nlm.nih.gov/pubmed/20577596