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Towards an anti-fibrotic therapy for scleroderma: targeting myofibroblast differentiation and recruitment
BACKGROUND: In response to normal tissue injury, fibroblasts migrate into the wound where they synthesize and remodel new extracellular matrix. The fibroblast responsible for this process is called the myofibroblast, which expresses the highly contractile protein α-smooth muscle actin (α-SMA). In no...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890590/ https://www.ncbi.nlm.nih.gov/pubmed/20507556 http://dx.doi.org/10.1186/1755-1536-3-8 |