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Two four-marker haplotypes on 7q36.1 region indicate that the potassium channel gene HERG1 (KCNH2, Kv11.1) is related to schizophrenia: a case control study

BACKGROUND: The pathobiology of schizophrenia is still unclear. Its current treatment mainly depends on antipsychotic drugs. A leading adverse effect of these medications is the acquired long QT syndrome, which results from the blockade of cardiac HERG1 channels (human ether-a-go-go-related gene pot...

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Detalles Bibliográficos
Autores principales: Atalar, Fatmahan, Acuner, Tufan Tevfik, Cine, Naci, Oncu, Fatih, Yesilbursa, Dogan, Ozbek, Ugur, Turkcan, Solmaz
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890623/
https://www.ncbi.nlm.nih.gov/pubmed/20507645
http://dx.doi.org/10.1186/1744-9081-6-27