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Two four-marker haplotypes on 7q36.1 region indicate that the potassium channel gene HERG1 (KCNH2, Kv11.1) is related to schizophrenia: a case control study
BACKGROUND: The pathobiology of schizophrenia is still unclear. Its current treatment mainly depends on antipsychotic drugs. A leading adverse effect of these medications is the acquired long QT syndrome, which results from the blockade of cardiac HERG1 channels (human ether-a-go-go-related gene pot...
Autores principales: | Atalar, Fatmahan, Acuner, Tufan Tevfik, Cine, Naci, Oncu, Fatih, Yesilbursa, Dogan, Ozbek, Ugur, Turkcan, Solmaz |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890623/ https://www.ncbi.nlm.nih.gov/pubmed/20507645 http://dx.doi.org/10.1186/1744-9081-6-27 |
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