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Angiotensin II and the ERK pathway mediate the induction of myocardin by hypoxia in cultured rat neonatal cardiomyocytes

Hypoxic injury to cardiomyocytes is a stress that causes cardiac pathology through cardiac-restricted gene expression. SRF (serum-response factor) and myocardin are important for cardiomyocyte growth and differentiation in response to myocardial injuries. Previous studies have indicated that AngII (...

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Detalles Bibliográficos
Autores principales: Chiu, Chiung-Zuan, Wang, Bao-Wei, Chung, Tun-Hui, Shyu, Kou-Gi
Formato: Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890999/
https://www.ncbi.nlm.nih.gov/pubmed/20446923
http://dx.doi.org/10.1042/CS20100084