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Overloading ion-exchange membranes as a purification step for monoclonal antibodies
The present study examined the overloading of ion-exchange membrane adsorbers, a form of frontal chromatography, as the final purification step in the production of mAbs (monoclonal antibodies) produced from CHO (Chinese-hamster ovary) cells. Preferential binding of impurities over antibody product...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Portland Press Ltd.
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891000/ https://www.ncbi.nlm.nih.gov/pubmed/20497123 http://dx.doi.org/10.1042/BA20090369 |