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Overloading ion-exchange membranes as a purification step for monoclonal antibodies

The present study examined the overloading of ion-exchange membrane adsorbers, a form of frontal chromatography, as the final purification step in the production of mAbs (monoclonal antibodies) produced from CHO (Chinese-hamster ovary) cells. Preferential binding of impurities over antibody product...

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Detalles Bibliográficos
Autores principales:	Brown, Arick, Bill, Jerome, Tully, Timothy, Radhamohan, Asha, Dowd, Chris
Formato:	Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891000/ https://www.ncbi.nlm.nih.gov/pubmed/20497123 http://dx.doi.org/10.1042/BA20090369

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