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Autophagy inhibition enhances vorinostat-induced apoptosis via ubiquitinated protein accumulation

Autophagy is an evolutionarily conserved cell survival pathway that enables cells to recoup ATP and other critical biosynthetic molecules during nutrient deprivation or exposure to hypoxia, which are hallmarks of the tumour microenvironment. Autophagy has been implicated as a potential mechanism of...

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Detalles Bibliográficos
Autores principales: Carew, Jennifer S, Medina, Ernest C, Esquivel II, Juan A, Mahalingam, Devalingam, Swords, Ronan, Kelly, Kevin, Zhang, Hui, Huang, Peng, Mita, Alain C, Mita, Monica M, Giles, Francis J, Nawrocki, Steffan T
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891399/
https://www.ncbi.nlm.nih.gov/pubmed/19583815
http://dx.doi.org/10.1111/j.1582-4934.2009.00832.x