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Autophagy inhibition enhances vorinostat-induced apoptosis via ubiquitinated protein accumulation
Autophagy is an evolutionarily conserved cell survival pathway that enables cells to recoup ATP and other critical biosynthetic molecules during nutrient deprivation or exposure to hypoxia, which are hallmarks of the tumour microenvironment. Autophagy has been implicated as a potential mechanism of...
Autores principales: | , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891399/ https://www.ncbi.nlm.nih.gov/pubmed/19583815 http://dx.doi.org/10.1111/j.1582-4934.2009.00832.x |