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Validation of dot blot hybridization and denaturing high performance liquid chromatography as reliable methods for TP53 codon 72 genotyping in molecular epidemiologic studies

BACKGROUND: Mutations in TP53 are common events during carcinogenesis. In addition to gene mutations, several reports have focused on TP53 polymorphisms as risk factors for malignant disease. Many studies have highlighted that the status of the TP53 codon 72 polymorphism could influence cancer susce...

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Detalles Bibliográficos
Autores principales: Rabachini, Tatiana, Trottier, Helen, Franco, Eduardo L, Villa, Luisa L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891603/
https://www.ncbi.nlm.nih.gov/pubmed/20504317
http://dx.doi.org/10.1186/1471-2156-11-44