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Alterations in osteoclast function and phenotype induced by different inhibitors of bone resorption - implications for osteoclast quality

BACKGROUND: Normal osteoclasts resorb bone by secretion of acid and proteases. Recent studies of patients with loss of function mutations affecting either of these processes have indicated a divergence in osteoclastic phenotypes. These difference in osteoclast phenotypes may directly or indirectly h...

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Detalles Bibliográficos
Autores principales: Neutzsky-Wulff, Anita V, Sørensen, Mette G, Kocijancic, Dino, Leeming, Diana J, Dziegiel, Morten H, Karsdal, Morten A, Henriksen, Kim
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891608/
https://www.ncbi.nlm.nih.gov/pubmed/20515459
http://dx.doi.org/10.1186/1471-2474-11-109