Cargando…
Alterations in osteoclast function and phenotype induced by different inhibitors of bone resorption - implications for osteoclast quality
BACKGROUND: Normal osteoclasts resorb bone by secretion of acid and proteases. Recent studies of patients with loss of function mutations affecting either of these processes have indicated a divergence in osteoclastic phenotypes. These difference in osteoclast phenotypes may directly or indirectly h...
Autores principales: | Neutzsky-Wulff, Anita V, Sørensen, Mette G, Kocijancic, Dino, Leeming, Diana J, Dziegiel, Morten H, Karsdal, Morten A, Henriksen, Kim |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891608/ https://www.ncbi.nlm.nih.gov/pubmed/20515459 http://dx.doi.org/10.1186/1471-2474-11-109 |
Ejemplares similares
-
Screening of protein kinase inhibitors identifies PKC inhibitors as inhibitors of osteoclastic acid secretion and bone resorption
por: Sørensen, Mette G, et al.
Publicado: (2010) -
Osteoclasts degrade bone and cartilage knee joint compartments through different resorption processes
por: Löfvall, Henrik, et al.
Publicado: (2018) -
Dissociation of Bone Resorption and Bone Formation in Adult Mice with a Non-Functional V-ATPase in Osteoclasts Leads to Increased Bone Strength
por: Henriksen, Kim, et al.
Publicado: (2011) -
Osteoclasts secrete osteopontin into resorption lacunae during bone resorption
por: Luukkonen, Jani, et al.
Publicado: (2019) -
Septins are critical regulators of osteoclastic bone resorption
por: Møller, Anaïs M. J., et al.
Publicado: (2018)