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Resveratrol suppresses IGF-1 induced human colon cancer cell proliferation and elevates apoptosis via suppression of IGF-1R/Wnt and activation of p53 signaling pathways

BACKGROUND: Obesity is a global phenomenon and is associated with various types of cancer, including colon cancer. There is a growing interest for safe and effective bioactive compounds that suppress the risk for obesity-promoted colon cancer. Resveratrol (trans-3, 4', 5,-trihydroxystilbene), a...

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Detalles Bibliográficos
Autores principales: Vanamala, Jairam, Reddivari, Lavanya, Radhakrishnan, Sridhar, Tarver, Chris
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891636/
https://www.ncbi.nlm.nih.gov/pubmed/20504360
http://dx.doi.org/10.1186/1471-2407-10-238