Putative tumour-suppressor gene DAB2 is frequently down regulated by promoter hypermethylation in nasopharyngeal carcinoma

BACKGROUND: Human Disabled-2 (DAB2), is a multi-function signalling molecule that it is frequently down-regulated in human cancers. We aimed to investigate the possible tumour suppressor effect of DAB2 in nasopharyngeal carcinoma (NPC). METHODS: We studied the expression of DAB2 in NPC cell lines, x...

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Detalles Bibliográficos
Autores principales: Tong, Joanna H, Ng, David C, Chau, Shuk L, So, Ken K, Leung, Patrick P, Lee, Tin L, Lung, Raymond W, Chan, Michael W, Chan, Anthony W, Lo, Kwok W, To, Ka F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891638/
https://www.ncbi.nlm.nih.gov/pubmed/20525238
http://dx.doi.org/10.1186/1471-2407-10-253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891638/
https://www.ncbi.nlm.nih.gov/pubmed/20525238
http://dx.doi.org/10.1186/1471-2407-10-253

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