Cargando…

Putative tumour-suppressor gene DAB2 is frequently down regulated by promoter hypermethylation in nasopharyngeal carcinoma

BACKGROUND: Human Disabled-2 (DAB2), is a multi-function signalling molecule that it is frequently down-regulated in human cancers. We aimed to investigate the possible tumour suppressor effect of DAB2 in nasopharyngeal carcinoma (NPC). METHODS: We studied the expression of DAB2 in NPC cell lines, x...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tong, Joanna H, Ng, David C, Chau, Shuk L, So, Ken K, Leung, Patrick P, Lee, Tin L, Lung, Raymond W, Chan, Michael W, Chan, Anthony W, Lo, Kwok W, To, Ka F
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891638/ https://www.ncbi.nlm.nih.gov/pubmed/20525238 http://dx.doi.org/10.1186/1471-2407-10-253

Ejemplares similares

TFPI-2 is a putative tumor suppressor gene frequently inactivated by promoter hypermethylation in nasopharyngeal carcinoma
por: Wang, Shumin, et al.
Publicado: (2010)

Frequent Loss Expression of Dab2 and Promotor Hypermethylation in Human Cancers: A Meta-Analysis and Systematic Review
por: Zhang, Ziyin, et al.
Publicado: (2014)

Putative tumour suppressor gene necdin is hypermethylated and mutated in human cancer
por: De Faveri, L E, et al.
Publicado: (2013)

Metallothionein III (MT3) is a putative tumor suppressor gene that is frequently inactivated in pediatric acute myeloid leukemia by promoter hypermethylation
por: Tao, Yan-Fang, et al.
Publicado: (2014)

Cytochrome b5 reductase 2 is a novel candidate tumor suppressor gene frequently inactivated by promoter hypermethylation in human nasopharyngeal carcinoma
por: Xiao, Xue, et al.
Publicado: (2013)

Frequent Promoter Hypermethylation of the APC and RASSF1A Tumour Suppressors in Parathyroid Tumours
por: Juhlin, C. Christofer, et al.
Publicado: (2010)

To Dab or Not to Dab: Rising Concerns Regarding the Toxicity of Cannabis Concentrates
por: Alzghari, Saeed K, et al.
Publicado: (2017)

ECRG4 is a candidate tumor suppressor gene frequently hypermethylated in colorectal carcinoma and glioma
por: Götze, Silke, et al.
Publicado: (2009)

ECRG4 acts as a tumor suppressor gene frequently hypermethylated in human breast cancer
por: Tang, Gao-Yan, et al.
Publicado: (2019)

Tumor suppressor genes on frequently deleted chromosome 3p in nasopharyngeal carcinoma
por: Chen, Juan, et al.
Publicado: (2012)

Protocadherin 17 is a tumor suppressor and is frequently methylated in nasopharyngeal carcinoma
por: He, Ya, et al.
Publicado: (2019)

EBV‐encoded miRNAs target ATM‐mediated response in nasopharyngeal carcinoma
por: Lung, Raymond W‐M, et al.
Publicado: (2018)

Dynamic expression of Dab2 in the mouse embryonic central nervous system
por: Cheung, Kwok-Kuen, et al.
Publicado: (2008)

Protocadherin 17 Is a Tumor Suppressor and Is Frequently Methylated in Nasopharyngeal Carcinoma [Retraction]
Publicado: (2020)

DAB2IP Is a Bifunctional Tumor Suppressor That Regulates Wild-Type RAS and Inflammatory Cascades in KRAS Mutant Colon Cancer
por: Miller, Abigail L., et al.
Publicado: (2023)

Frequent Down Regulation of the Tumor Suppressor Gene A20 in Multiple Myeloma
por: Troppan, Katharina, et al.
Publicado: (2015)

A mechanism for cell non-autonomous inactivation of the tumor suppressor DAB2IP
por: Bellazzo, Arianna, et al.
Publicado: (2018)

Hypermethylation of tumor suppressor lncRNA MEF2C-AS1 frequently happened in patients at all stages of colorectal carcinogenesis
por: Qian, Sangni, et al.
Publicado: (2022)

Potential diagnostic and prognostic values of detecting promoter hypermethylation in the serum of patients with gastric cancer
por: Leung, W K, et al.
Publicado: (2005)

Hypermethylation of genes in testicular embryonal carcinomas
por: Cheung, Hoi-Hung, et al.
Publicado: (2016)

Promoter Hypermethylation of Tumor Suppressor Genes Located on Short Arm of the Chromosome 3 as Potential Biomarker for the Diagnosis of Nasopharyngeal Carcinoma
por: Lao, Thuan Duc, et al.
Publicado: (2021)

Reprimo, a Potential p53-Dependent Tumor Suppressor Gene, Is Frequently Hypermethylated in Estrogen Receptor α-Positive Breast Cancer
por: Buchegger, Kurt, et al.
Publicado: (2017)

CHD5 is down-regulated through promoter hypermethylation in gastric cancer
por: Wang, Xian, et al.
Publicado: (2009)

Bacteria pathogens drive host colonic epithelial cell promoter hypermethylation of tumor suppressor genes in colorectal cancer
por: Xia, Xiaoxuan, et al.
Publicado: (2020)

OPCML Is a Broad Tumor Suppressor for Multiple Carcinomas and Lymphomas with Frequently Epigenetic Inactivation
por: Cui, Yan, et al.
Publicado: (2008)

DAB-quant: An open-source digital system for quantifying immunohistochemical staining with 3,3′-diaminobenzidine (DAB)
por: Patel, Sneh, et al.
Publicado: (2022)

Cigarette smoke affects the onco-suppressor DAB2IP expression in bronchial epithelial cells of COPD patients
por: Anzalone, Giulia, et al.
Publicado: (2019)

Global DNA Hypermethylation in Down Syndrome Placenta
por: Jin, Shengnan, et al.
Publicado: (2013)

EBV–encoded miRNAs can sensitize nasopharyngeal carcinoma to chemotherapeutic drugs by targeting BRCA1
por: Lung, Raymond Wai‐Ming, et al.
Publicado: (2020)

Wnt signalling in human breast cancer: expression of the putative Wnt inhibitor Dickkopf-3 (DKK3) is frequently suppressed by promoter hypermethylation in mammary tumours
por: Veeck, Jürgen, et al.
Publicado: (2008)

Frequent promoter hypermethylation of RASSF1A and CASP8 in neuroblastoma
por: Lázcoz, Paula, et al.
Publicado: (2006)

Transgelin gene is frequently downregulated by promoter DNA hypermethylation in breast cancer
por: Sayar, Nilufer, et al.
Publicado: (2015)

Frequent hypermethylation of orphan CpG islands with enhancer activity in cancer
por: Bae, Min Gyun, et al.
Publicado: (2016)

Association of frequent hypermethylation with high grade histological subtype in lung adenocarcinoma
por: Ito, Yuki, et al.
Publicado: (2023)

Correction: OPCML Is a Broad Tumor Suppressor for Multiple Carcinomas and Lymphomas with Frequently Epigenetic Inactivation
por: Cui, Yan, et al.
Publicado: (2008)

Absence of cyclin D2 expression is associated with promoter hypermethylation in gastric cancer
por: Yu, J, et al.
Publicado: (2003)

DAB2IP in cancer
por: Liu, Liang, et al.
Publicado: (2015)

Dabbing-Induced Hypersensitivity Pneumonitis
por: Haddad, Ibrahim, et al.
Publicado: (2021)

Cannabis dabbing: An emerging trend
por: Mullins, Mary Frances
Publicado: (2021)

Frequent Epigenetic Suppression of Tumor Suppressor Gene Glutathione Peroxidase 3 by Promoter Hypermethylation and Its Clinical Implication in Clear Cell Renal Cell Carcinoma
por: Liu, Qianling, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_hu95sqmojs9vajqc1jo8u6hd1e