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Methylthioadenosine (MTA) inhibits melanoma cell proliferation and in vivo tumor growth

BACKGROUND: Melanoma is the most deadly form of skin cancer without effective treatment. Methylthioadenosine (MTA) is a naturally occurring nucleoside with differential effects on normal and transformed cells. MTA has been widely demonstrated to promote anti-proliferative and pro-apoptotic responses...

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Detalles Bibliográficos
Autores principales: Andreu-Pérez, Pedro, Hernandez-Losa, Javier, Moliné, Teresa, Gil, Rosa, Grueso, Judit, Pujol, Anna, Cortés, Javier, Avila, Matias A, Recio, Juan A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891639/
https://www.ncbi.nlm.nih.gov/pubmed/20529342
http://dx.doi.org/10.1186/1471-2407-10-265