DR5-mediated DISC controls caspase-8 cleavage and initiation of apoptosis in human glioblastomas

To explore the molecular mechanisms by which glioblastomas are resistant to tumour necrosis factor-related apoptosis-inducing ligand (TRAIL), we examined TRAIL signalling pathways in the tumours. TRAIL has four membrane-anchored receptors, death receptor 4/5 (DR4/5) and decoy receptor 1/2 (DcR1/2)....

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Detalles Bibliográficos
Autores principales: Bellail, Anita C, Tse, Margaret C L, Song, Jin H, Phuphanich, Surasak, Olson, Jeffrey J, Sun, Shi Yong, Hao, Chunhai
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891654/
https://www.ncbi.nlm.nih.gov/pubmed/19432816
http://dx.doi.org/10.1111/j.1582-4934.2009.00777.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891654/
https://www.ncbi.nlm.nih.gov/pubmed/19432816
http://dx.doi.org/10.1111/j.1582-4934.2009.00777.x

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