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High cell density cultivation and recombinant protein production with Escherichia coli in a rocking-motion-type bioreactor

BACKGROUND: Single-use rocking-motion-type bag bioreactors provide advantages compared to standard stirred tank bioreactors by decreased contamination risks, reduction of cleaning and sterilization time, lower investment costs, and simple and cheaper validation. Currently, they are widely used for c...

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Detalles Bibliográficos
Autores principales: Glazyrina, Julia, Materne, Eva-Maria, Dreher, Thomas, Storm, Dirk, Junne, Stefan, Adams, Thorsten, Greller, Gerhard, Neubauer, Peter
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891675/
https://www.ncbi.nlm.nih.gov/pubmed/20509968
http://dx.doi.org/10.1186/1475-2859-9-42