Plato's Cave Algorithm: Inferring Functional Signaling Networks from Early Gene Expression Shadows

Improving the ability to reverse engineer biochemical networks is a major goal of systems biology. Lesions in signaling networks lead to alterations in gene expression, which in principle should allow network reconstruction. However, the information about the activity levels of signaling proteins co...

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Detalles Bibliográficos
Autores principales: Shimoni, Yishai, Fink, Marc Y., Choi, Soon-gang, Sealfon, Stuart C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891706/
https://www.ncbi.nlm.nih.gov/pubmed/20585619
http://dx.doi.org/10.1371/journal.pcbi.1000828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891706/
https://www.ncbi.nlm.nih.gov/pubmed/20585619
http://dx.doi.org/10.1371/journal.pcbi.1000828

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