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The polymorphism rs3024505 proximal to IL-10 is associated with risk of ulcerative colitis and Crohns disease in a Danish case-control study

BACKGROUND: Crohns disease (CD) and ulcerative colitis (UC) are characterized by a dysregulated inflammatory response to normal constituents of the intestinal flora in the genetically predisposed host. Heme oxygenase-1 (HO-1/HMOX1) is a powerful anti-inflammatory and anti-oxidant enzyme, whereas the...

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Detalles Bibliográficos
Autores principales: Andersen, Vibeke, Ernst, Anja, Christensen, Jane, Østergaard, Mette, Jacobsen, Bent A, Tjønneland, Anne, Krarup, Henrik B, Vogel, Ulla
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891714/
https://www.ncbi.nlm.nih.gov/pubmed/20509889
http://dx.doi.org/10.1186/1471-2350-11-82