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The polymorphism rs3024505 proximal to IL-10 is associated with risk of ulcerative colitis and Crohns disease in a Danish case-control study
BACKGROUND: Crohns disease (CD) and ulcerative colitis (UC) are characterized by a dysregulated inflammatory response to normal constituents of the intestinal flora in the genetically predisposed host. Heme oxygenase-1 (HO-1/HMOX1) is a powerful anti-inflammatory and anti-oxidant enzyme, whereas the...
Autores principales: | Andersen, Vibeke, Ernst, Anja, Christensen, Jane, Østergaard, Mette, Jacobsen, Bent A, Tjønneland, Anne, Krarup, Henrik B, Vogel, Ulla |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891714/ https://www.ncbi.nlm.nih.gov/pubmed/20509889 http://dx.doi.org/10.1186/1471-2350-11-82 |
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