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Antiproliferative effect of growth hormone-releasing hormone (GHRH) antagonist on ovarian cancer cells through the EGFR-Akt pathway

BACKGROUND: Antagonists of growth hormone-releasing hormone (GHRH) are being developed for the treatment of various human cancers. METHODS: MTT assay was used to test the proliferation of SKOV3 and CaOV3. The splice variant expression of GHRH receptors was examined by RT-PCR. The expression of prote...

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Detalles Bibliográficos
Autores principales: Guo, Jian, Schally, Andrew V, Zarandi, Marta, Varga, Jozsef, Leung, Peter CK
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891788/
https://www.ncbi.nlm.nih.gov/pubmed/20509930
http://dx.doi.org/10.1186/1477-7827-8-54