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Antiproliferative effect of growth hormone-releasing hormone (GHRH) antagonist on ovarian cancer cells through the EGFR-Akt pathway
BACKGROUND: Antagonists of growth hormone-releasing hormone (GHRH) are being developed for the treatment of various human cancers. METHODS: MTT assay was used to test the proliferation of SKOV3 and CaOV3. The splice variant expression of GHRH receptors was examined by RT-PCR. The expression of prote...
Autores principales: | Guo, Jian, Schally, Andrew V, Zarandi, Marta, Varga, Jozsef, Leung, Peter CK |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891788/ https://www.ncbi.nlm.nih.gov/pubmed/20509930 http://dx.doi.org/10.1186/1477-7827-8-54 |
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