Tandem E2F Binding Sites in the Promoter of the p107 Cell Cycle Regulator Control p107 Expression and Its Cellular Functions

The retinoblastoma tumor suppressor (Rb) is a potent and ubiquitously expressed cell cycle regulator, but patients with a germline Rb mutation develop a very specific tumor spectrum. This surprising observation raises the possibility that mechanisms that compensate for loss of Rb function are presen...

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Detalles Bibliográficos
Autores principales: Burkhart, Deborah L., Wirt, Stacey E., Zmoos, Anne-Flore, Kareta, Michael S., Sage, Julien
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891812/
https://www.ncbi.nlm.nih.gov/pubmed/20585628
http://dx.doi.org/10.1371/journal.pgen.1001003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891812/
https://www.ncbi.nlm.nih.gov/pubmed/20585628
http://dx.doi.org/10.1371/journal.pgen.1001003

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