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Role of PKR and Type I IFNs in Viral Control during Primary and Secondary Infection

Type I interferons (IFNs) are known to mediate viral control, and also promote survival and expansion of virus-specific CD8(+) T cells. However, it is unclear whether signaling cascades involved in eliciting these diverse cellular effects are also distinct. One of the best-characterized anti-viral s...

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Detalles Bibliográficos
Autores principales: Nakayama, Yumi, Plisch, Erin H., Sullivan, Jeremy, Thomas, Chester, Czuprynski, Charles J., Williams, Bryan R. G., Suresh, M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891951/
https://www.ncbi.nlm.nih.gov/pubmed/20585572
http://dx.doi.org/10.1371/journal.ppat.1000966