Mechanism of Inhibition of MMTV-neu and MMTV-wnt1 induced mammary oncogenesis by RARα agonist AM580

We hypothesized that specific activation of a single retinoic acid receptor, RARα without direct and concurrent activation of RARβ and γ, will inhibit mammary tumor oncogenesis in murine models relevant to human cancer. Fifty uniparous MMTV-neu and 50 nuliparous MMTV-wnt1 transgenic mice were treate...

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Detalles Bibliográficos
Autores principales: Lu, Yongke, Bertran, Silvina, Samuels, Tracey-Ann, Mira-y-Lopez, Rafael, Farias, Eduardo
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891995/
https://www.ncbi.nlm.nih.gov/pubmed/20453882
http://dx.doi.org/10.1038/onc.2010.119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891995/
https://www.ncbi.nlm.nih.gov/pubmed/20453882
http://dx.doi.org/10.1038/onc.2010.119

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