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The Ability to Generate Senescent Progeny as a Mechanism Underlying Breast Cancer Cell Heterogeneity

BACKGROUND: Breast cancer is a remarkably heterogeneous disease. Luminal, basal-like, “normal-like”, and ERBB2+ subgroups were identified and were shown to have different prognoses. The mechanisms underlying this heterogeneity are poorly understood. In our study, we explored the role of cellular dif...

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Detalles Bibliográficos
Autores principales: Mumcuoglu, Mine, Bagislar, Sevgi, Yuzugullu, Haluk, Alotaibi, Hani, Senturk, Serif, Telkoparan, Pelin, Gur-Dedeoglu, Bala, Cingoz, Burcu, Bozkurt, Betul, Tazebay, Uygar H., Yulug, Isik G., Akcali, K. Can, Ozturk, Mehmet
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891998/
https://www.ncbi.nlm.nih.gov/pubmed/20585577
http://dx.doi.org/10.1371/journal.pone.0011288