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Increased Cell Migration and Plasticity in Nrf2 Deficient Cancer Cell Lines

Nuclear Factor (erythroid-derived 2)-like 2 (Nrf2) expression is deregulated in many cancers. Genetic and biochemical approaches coupled with functional assays in cultured cells were used to explore the consequence of Nrf2 repression. Nrf2 suppression by Keap1-directed ubiquitylation or expression o...

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Detalles Bibliográficos
Autores principales: Rachakonda, Girish, Sekhar, Konjeti R., Jowhar, Dawit, Samson, Philip C., Wikswo, John P., Beauchamp, R. Daniel, Datta, Pran K., Freeman, Michael L.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892014/
https://www.ncbi.nlm.nih.gov/pubmed/20440267
http://dx.doi.org/10.1038/onc.2010.118