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Increased Cell Migration and Plasticity in Nrf2 Deficient Cancer Cell Lines
Nuclear Factor (erythroid-derived 2)-like 2 (Nrf2) expression is deregulated in many cancers. Genetic and biochemical approaches coupled with functional assays in cultured cells were used to explore the consequence of Nrf2 repression. Nrf2 suppression by Keap1-directed ubiquitylation or expression o...
Autores principales: | Rachakonda, Girish, Sekhar, Konjeti R., Jowhar, Dawit, Samson, Philip C., Wikswo, John P., Beauchamp, R. Daniel, Datta, Pran K., Freeman, Michael L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892014/ https://www.ncbi.nlm.nih.gov/pubmed/20440267 http://dx.doi.org/10.1038/onc.2010.118 |
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