Cargando…
Androgen Excess Produces Systemic Oxidative Stress and Predisposes to β-Cell Failure in Female Mice
In women, excess production of the male hormone, testosterone (T), is accompanied by insulin resistance. However, hyperandrogenemia is also associated with β-cell dysfunction and type 2 diabetes raising the possibility that androgen receptor (AR) activation predisposes to β-cell failure. Here, we te...
| Autores principales: | , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892018/ https://www.ncbi.nlm.nih.gov/pubmed/20585581 http://dx.doi.org/10.1371/journal.pone.0011302 |