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The Minimal Autoinhibited Unit of the Guanine Nucleotide Exchange Factor Intersectin

Intersectin-1L is a member of the Dbl homology (DH) domain guanine nucleotide exchange factors (GEF) which control Rho-family GTPase signaling. Intersectin-1L is a GEF that is specific for Cdc42. It plays an important role in endocytosis, and is regulated by several partners including the actin regu...

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Detalles Bibliográficos
Autores principales: Ahmad, K. Farid, Lim, Wendell A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892021/
https://www.ncbi.nlm.nih.gov/pubmed/20585582
http://dx.doi.org/10.1371/journal.pone.0011291